Bioorganic synthesis

Group Prof. Dr. Oliver Seitz

Publications

112. "Promoting strand exchange in a DNA-templated transfer reaction"
Julia Michaelis, Atsushi Maruyama, Oliver Seitz*, Chem. Commun. 2013, 49, 618-620; Chem. Commun. 2013, 49, 618-620. (DOI: 10.1039/c2c36162k)

111. "Bioorthogonal reactions challenged: DNA templated native chemical ligation during PCR"
A. Roloff, O.Seitz*, Chem. Sci. 2012; Chem. Sci. 2012. (DOI: 10.1039/c2sc20961f)

110. "Multivalency as a Chemical Organization and Action Principle"
C. Fasting, C.A. Schalley, M. Weber, O. Seitz, S. Hecht, B. Koksch, J. Dernedde, C. Graf, E.-W. Knapp, R. Haag*, Angew. Chem. Int. Ed. 2012, 54, 10472-10498; Angew. Chem. Int. Ed. 2012, 54, 10472-10498. (DOI: 10.1021/bc300249f)

109. "PNA FIT-Probes for the Dual Color Imaging of Two Viral mRNA Targets in Influenca H1N1 Infected Live cells"
S. Kummer, A. Knoll, E. Socher, L. Bethge, A. Herrmann*, O. Seitz*, Bioconjugate Chem. 2012, 23, 2051-2060; Bioconjugate Chem. 2012, 23, 2051-2060. (DOI: 10.1021/bc300249f)

108. "Single Labeled DNA FIT probes for Avoiding False-Positive Signaling in the detection of DNA/RNA in qPCR or cell media"
F. Hövelmann, L. Bethge, O. Seitz*, ChemBioChem 2012, 13, 2072-2081; ChemBioChem 2012, 13, 2072-2081. (DOI: 10.1002/cbic.201200397)

107. "Dual fluorophore PNA FIT-probes - extremely responsive and bright hybridization probes for the sensitive detection of DNA and RNA"
E. Socher, A. Knoll, O. Seitz*, Org. Biomol. Chem. 2012, 10, 7363-7371; Org. Biomol. Chem. 2012, 10, 7363-7371. (DOI: 10.1039/c2ob25925g)

106. "Consecutive Signal Amplification for DNA Detection Based on De Novo Fluorophore Synthesis and Host–Guest Chemistry"
X.-H. Chen, A. Roloff, O. Seitz*, Angew. Chem. 2012, 124 (18), 4556-4561; Angew. Chem. Int. Ed. 2012, 51 (18), 4479-4483. (DOI: 10.1002/anie.201108845)

105. "PNA-sugar conjugates as tools for the spatial screening of carbohydrate–lectin interactions"
C. Scheibe, O. Seitz*, Pure Appl. Chem. 2012, 84 (1), 77-85. (DOI: 10.1351/PAC-CON-11-08-07)

104. "Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs"
A. G. Torres, M. M. Fabani, E. Vigorito, D. Williams, N. Al-Obaidi, F. Wojciechowski, R. H. E. Hudson, O. Seitz, M. J. Gait*, Nucl. Acids Res. 2012, 40 (5), 2152-2167. (DOI: 10.1093/nar/gkr885)

103. "Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding"
M. Shan, A. Bujotzek, F. Abendroth, A. Wellner, R. Gust, O. Seitz, M. Weber, R. Haag*, ChemBioChem 2011, 12 (17), 2587-2598. (DOI: 10.1002/cbic.201100529)

102. "Synthesis of Nucleic Acid–Peptide Conjugates Targeted to Proteins"
A. Erben, O. Seitz*, Isr. J. Chem. 2011, 51 (8-9), 876-884. (DOI: 10.1002/ijch.201100086)

101. "DNA-Controlled Bivalent Presentation of Ligands for the Estrogen Receptor"
F. Abendroth, A. Bujotzek, M. Shan, R. Haag, M. Weber, O. Seitz*, Angew. Chem. 2011, 123 (37), 8751-8755; Angew. Chem. Int. Ed. 2011, 50 (37), 8592-8596. (DOI: 10.1002/anie.201101655)

100. "DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides"
A. Erben, T. N. Grossmann, O. Seitz*, Bioorg. Med. Chem. Lett. 2011, 21 (17), 4993-4997. (DOI: 10.1016/j.bmcl.2011.05.027)

99. "DNA-guided display of proteins and protein ligands for the interrogation of biology"
F. Diezmann, O. Seitz*, Chem. Soc. Rev. 2011, 40 (12), 5789-5801. (DOI: 10.1039/C1CS15054E)

98. "Ascorbate as an Alternative to Thiol Additives in Native Chemical Ligation"
H. Rohde, J. Schmalisch, Z. Harpaz, F. Diezmann, O. Seitz*, ChemBioChem 2011, 12 (9), 1396-1400. (DOI: 10.1002/cbic.201100179)

97. "DNA as a Molecular Ruler: Interrogation of a Tandem SH2 Domain with Self-Assembled, Bivalent DNA–Peptide Complexes"
H. Eberhard, F. Diezmann, O. Seitz*, Angew. Chem. 2011, 123 (18), 4232-4236; Angew. Chem. Int. Ed. 2011, 50 (18), 4146-4150. (DOI: 10.1002/anie.201007593)

96. "DNA-Triggered Synthesis and Bioactivity of Proapoptotic Peptides"
A. Erben, T. N. Grossmann, O. Seitz*, Angew. Chem. 2011, 123 (12), 2880-2884; Angew. Chem. Int. Ed. 2011, 50 (12), 2828-2832. (DOI: 10.1002/anie.201007103)

95. "DNA-programmed spatial screening of carbohydrate–lectin interactions"
C. Scheibe, A. Bujotzek, J. Dernedde, M. Weber, O. Seitz*, Chem. Sci. 2011, 2 (4), 770-775. (DOI: 10.1039/C0SC00565G)

94. "Fluorescence Imaging of Influenza H1N1 mRNA in Living Infected Cells Using Single-Chromophore FIT-PNA"
S. Kummer, A. Knoll, E. Socher, L. Bethge, A. Herrmann*, O. Seitz*, Angew. Chem. 2011, 123 (8), 1972-1975; Angew. Chem. Int. Ed. 2011, 50 (8), 1931-1934. (DOI: 10.1002/anie.201005902)

93. "9-Fluorenylmethoxycarbonyl-Based Solid-Phase Synthesis of Peptide α-Thioesters"
F. Mende, O. Seitz*, Angew. Chem. 2011, 123 (6), 1266-1274; Angew. Chem. Int. Ed. 2011, 50 (6), 1232-1240. (DOI: 10.1002/anie.201005180)

92. "Lipid Domain Specific Recruitment of Lipophilic Nucleic Acids: A Key for Switchable Functionalization of Membranes"
M. Loew, R. Springer, S. Scolari, F. Altenbrunn, O. Seitz, J. Liebscher, D. Huster, A. Herrmann, A. Arbuzova*, J. Am. Chem. Soc. 2010, 132 (45), 16066-16072. (DOI: 10.1021/ja105714r)

91. "Evolution of synthetic polymers (Commentary)"
A. Roloff, O. Seitz*, Artificial DNA: PNA & XNA 2010, 1 (2), 61-63. (DOI: 10.4161/adna.1.2.13501)

90. "Automated Fmoc-Based Solid-Phase Synthesis of Peptide Thioesters with Self-Purification Effect and Application in the Construction of Immobilized SH3 Domains"
F. Mende, M. Beisswenger, O. Seitz*, J. Am. Chem. Soc. 2010, 132, 32, 11110-11118.

89. "Invited review: Ligation - Desulfurization: A powerful combination in the synthesis of peptides and glycopeptides"
H. Rohde, O. Seitz*, Biopolymers (Pept. Sci.) 2010, 94, 4, 551-559.

88. "Native chemical ligation in the synthesis of internally modified oligonucleotide-peptide conjugates"
F. Diezmann, H. Eberhard, O. Seitz*, Biopolymers (Pept. Sci.) 2010, 94, 4, 397-404.

87. "Designed thiazole orange nucleotides that fluoresce upon matched hybridization of single labelled oligonucleotides"
L. Bethge, I. Singh, O. Seitz*, Org. Biomol. Chem. 2010, 2439-2448.

86. "Binaphthyl-DNA: Stacking and Fluorescence of a Nonplanar Aromatic Base Surrogate in DNA"
S. Hainke, O. Seitz*, Angew. Chem. 2009, 121, 44, 9399-8402; Angew. Chem. Int. Ed 2009, 48, 44, 8250-8253.

85. "Internal Cysteine Accelerates Thioester-Based Peptide Ligation"
C. Haase, O. Seitz*, Eur. J. Org. Chem. 2009, 2096-2101.

84. "Synthesis and evaluation of a netropsin–proximicin-hybrid library for DNA binding and cytotoxicity"
F. E. Wolter, L. Molinari, E. R. Socher, K. Schneider, G. Nicholson, W. Beil, O. Seitz, R. D. Süssmuth*, Bioorg. Med. Chem. Lett. 2009, 19, 14/15, 3811-3815.

83. "Total Synthesis of Proximicin A-C and Synthesis of New Furan-Based DNA Binding Agents"
F. E. Wolter, K. Schneider, B. P. Davies, E. R. Socher, G. Nicholson, O. Seitz, R. D. Süssmuth*, Org. Lett. 2009, 11, 13, 2804-2807.

82. "Nucleic acid-templated reactions: consequences of probe reactivity and readout strategy for amplified signaling and sequence selectivity"
T. N. Grossmann, O. Seitz*, Chem. Eur. J. 2009, 16, 20, 6723-6730.

81. "New aspects in fragmentation of peptide nucleic acids: comparison of positive and negative ions by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry"
M. Ziehe, T. N. Grossmann, O. Seitz, M. W. Linscheid*, Rapid Commun. Mass Spectrom. 2009, 2, 1132-1138.

80. "DNA and RNA controlled switching of protein kinase activity"
L. Röglin, F. Altenbrunn, O. Seitz*, ChemBioChem 2009, 10, 4, 758-765.

79. "Chemical control of biomolecular interaction modules"
F. Altenbrunn, T. N. Grossmann, C. Haase, F. Mende, L. Röglin, S. Thurley, O. Seitz*, Pure Appl. Chem. 2009, 81, 2, 273-284.

78. "FIT-probes in real-time PCR"
E. Socher, O. Seitz, Methods Mol. Biol. 2008, 429, 187-197. (DOI: 10.1007/978-1-60327-040-3_13)

77. "Low noise stem-less PNA beacons for sensitive DNA and RNA detection"
E. Socher, L. Bethge, A. Knoll, N. Jungnick, A. Herrmann, O. Seitz*, Angew. Chem. 2008, 120, 49, 9697-9701; Angew. Chem. Int. Ed 2008, 47, 49, 9555-9559.

76. "Target-catalyzed transfer reactions for the amplified detection of RNA"
T. N. Grossmann, L. Röglin, O. Seitz*, Angew. Chem. 2008, 120, 7228-7231; Angew. Chem. Int. Ed. 2008, 47, 7119-7122.

75. "Controlling the Activity of Peptides and Proteins with Nucleic Acids" (Emerging Area Review)
L. Röglin, O. Seitz*, Org. Biomol. Chem. 2008, 6, 3881-3887.

74. "Achieving Turnover in DNA-templated Reactions" (Mini Review)
T. N. Grossmann, A. Strohbach, O. Seitz*, ChemBioChem 2008, 9, 2185-2192.

73. "Native Chemical Ligation at Valine"
C. Haase, H. Rohde, O. Seitz*, Angew. Chem. 2008, 120, 36, 6912-6915; Angew. Chem. Int. Ed. 2008, 47, 36, 6807-6810.

72. "O-Allyl protection in the Fmoc-based synthesis of difficult PNA"
F. Altenbrunn, O. Seitz*, Org. Biomol. Chem. 2008, 6, 2493-2498.

71. "Proximicins A, B, and C - Antitumor Furan Analogues of Netropsin from the Marine Actinomycete Verrucosispora Induce Upregulation of p53 and the Cyclin Kinase Inhibitor p21"
K. Schneider, S. Keller, F. E. Wolter, L. Röglin, W. Beil, O. Seitz, G. Nicholson, C. Bruntner, J. Riedlinger, H.-P. Fiedler, R. D. Süssmuth*, Angew. Chem. 2008, 120, 3302-3305; Angew. Chem. Int. Ed. 2008, 47, 3258-3261.

70. "N->O-Acyl shift in Fmoc-based syntheses of phosphopeptides"
H. Eberhard, O. Seitz*, Org. Biomol. Chem. 2008, 6, 1349-1355.

69. "Mehr Spielraum für die Native Chemische Peptidkupplung" (Highlight)
C. Haase, O. Seitz*, Angew. Chem. 2008, 120, 1575-1579; Angew. Chem. Int. Ed. 2008, 47, 1553-1556.

68. "FIT-probes - Peptide nucleic acid (PNA) probes with a fluorescent base surrogate enable real-time DNA quantification and SNP discovery"
E. Socher, D. V. Jarikote, A. Knoll, L. Röglin, J. Burmeister, O.Seitz*, Analytical Biochemistry, 2008, 375, 2, 318-330.

67. "Nucleic Acid Modification in Fluorescence Technologies" (Editorial)
O. Seitz, Bioorg. Med. Chem. 2008, 16, 17-18.

66. "Inducing the Replacement of PNA in DNA·PNA Duplexes by DNA"
T. N. Grossmann, S. Sasaki, M. Ritzefeld, S. W. Choi, A. Maruyama and O. Seitz*, Bioorg. Med. Chem. 2008, 16, 34-39.

65. "Single Nucleotide Specific Detection of DNA by Native Chemical Ligation of Fluorescence labeled PNA-Probes"
C. Dose, O. Seitz*, Bioorg. Med. Chem. 2008, 16, 65-77.

64. "New Cyanine Dyes as Base Surrogates in PNA: Forced Intercalation Probes (FIT-Probes) for homogeneous SNP Detection"
L. Bethge, D. V. Jarikote, O. Seitz*, Bioorg. Med. Chem. 2008, 16, 114-125.

63. "Solid-Phase Synthesis of Peptide Thioesters with Self-Purification"
F. Mende, O. Seitz*, Angew. Chem. 2007, 119, 4661-4465; Angew. Chem. Int. Ed. 2007, 46, 4577-4582.

62. "Hairpin Peptide Beacon: Dual-labeled PNA-Peptide-Hybrids for Protein Detection"
S. Thurley, L. Röglin, O. Seitz*, J. Am. Chem. Soc. 2007, 129, 12693-12695.

61. "Synthesis of C-Aryl-Nucleosides and O-Aryl-Glycosides via Cuprate Glycosylation"
S. Hainke, I. Singh, J. Hemmings, O. Seitz*, J. Org. Chem. 2007, 72, 8811-8819.

60. "Triplex Molecular Beacons as Modular Probes for DNA Detection"
T. N. Grossmann, L. Röglin, O. Seitz*, Angew. Chem. 2007, 119, 5315-5318; Angew. Chem. Int. Ed.2007, 46, 5223-5225.

59. "DNA Made of Purines Only" (Commentary)
C. Arenz, O. Seitz*, Chem. Biol. 2007, 14, 467-469.

58. "DNA-Controlled Reversible Switching of Peptide Conformation and Bioactivity"
L. Röglin, M. R. Ahmadian, O. Seitz*, Angew. Chem. 2007, 119, 2759-2763; Angew. Chem. Int. Ed. 2007, 46, 2704-2707.

57. "Exploring Base-specific Optical Properties of the DNA Stain Thiazole Orange"
D.V. Jarikote, N. Krebs, S. Tannert, B. Röder, O. Seitz*, Chem. Eur. J. 2007, 13, 300-310.

56. "Chemical Synthesis of Glycopeptides"
C. Haase, O. Seitz*, Glycopeptides and Glycoproteins (Wittmann, Valentin; Ed.), 2006, 267, 1-36.

55. "DNA-Catalyzed Transfer of a Reporter Group"
T. N. Grossmann, O. Seitz*, J. Am. Chem. Soc., 2006, 128, 15596-15597.

54. "Diastereoselective Synthesis of b-/C/-Arylnucleosides from 1,2-Anhydrosugars"
I. Singh, O. Seitz*, Org. Lett. 2006, 8, 4319-4322.

53. "Diels-Alder Ligation of Peptides and Proteins"
A. Dantas de Araújo, J. M. Palomo, J. Cramer, O. Seitz, K. Alexandrov, H. Waldmann*, Chem. Eur. J. 2006, 12, 6095-6109.

52. "Reducing Product Inhibition in DNA-Template Controlled Ligation Reactions"
C. Dose, S. Ficht, O. Seitz*, Angew. Chem. 2006, 118, 5495-5499; Angew. Chem. Int. Ed. 2006, 45, 5369-5373.

51. "Large Dynamic Stokes Shift of DNA Intercalation Dye Thiazole Orange has Contribution from a High-Frequency Mode"
V. Karunakaran, J. L. Pérez Lustres, L. Zhao, N. P. Ernsting*, O. Seitz, J. Am. Chem. Soc. 2006, 128, 2954-2962.

50. "Concise synthesis of aryl-C-nucleosides by Friedel-Crafts alkylation"
S. Hainke, S. Arndt, O. Seitz*, Org. Biomol. Chem. 2005, 3, 4233-4238.

49. "Divergent and Linear Solid-Phase Synthesis of PNA Containing Thiazole Orange as Artificial Base"
D. V. Jarikote, O. Köhler, E. Socher, O. Seitz*, Eur. J. Org. Chem. 2005, 15, 3187–3195.

48. "Convergent Synthesis of Peptide Nucleic Acids by Native Chemical Ligation"
C. Dose, O. Seitz*, Org. Lett. 2005, 7, 4365-4368.

47. "As Fast and Selective as Enzymatic Ligations: Unpaired Nucleobases Increase the Selectivity of DNA-Controlled Native Chemical PNA-Ligation"
S. Ficht, C. Dose, O. Seitz*, ChemBioChem 2005, 6, 2098-2103.

46. "Forced Intercalation Probes (FIT-Probes) - Thiazole Orange as a Fluorescent Base in Peptide Nucleic Acids for Homogeneous SNP Detection"
O. Köhler, D. V. Jarikote, O. Seitz*, ChemBioChem 2005, 6, 69-77.

45. "Forced Intercalation as Tool in Gene Diagnostics and in Studying DNA-Protein Interactions"
O. Köhler, D. V. Jarikote, I. Singh, V.S. Parmar, E. Weinhold, O. Seitz*, Pure & Appl. Chem 2005, 77, 327-338.

44. "Ensemble hybridisation – a new method for exploring sequence dependent fluorescence of dye–nucleic acid conjugates"
O. Köhler, D. V. Jarikote, O. Seitz*, Chem. Commun. 2004, 2674-2675.

43. "Aromatic DNA Base Surrogates - Abasic Site Stabilization and High-Affinity Binding to a Base-Flipping DNA-Methyltransferase"
I. Singh, C. Beuck, A. Bhattacharya, W. Hecker, V.S. Parmar, E. Weinhold, O. Seitz*, Pure & Appl. Chem 2004, 76, 1563-1570.

42. "Direct Carbodiimide-Mediated Conjugation of Carboxylates Using Pyridinium p-Toluenesulfonate and Tertiary Amines as Additives"
S. Ficht, L. Röglin, M. Ziehe, D. Breyer, O. Seitz*, Synlett 2004, 2004, 2525-2528.

41. "Doubly-labeled Peptide Nucleic Acids (PNAs) as Probes for the Detection of DNA Point Mutations"
O. Köhler, S. Röttger, O. Seitz, Chemical Biology – A Practical Course (H. Waldmann, P. Janning; Eds.) 2004, Wiley-VCH, Weinheim, 35-44.

40. "DNA Synthesis and DNA Hybridization"
S. Ficht, W. Hecker, A. Mattes, O. Seitz, Chemical Biology – A Practical Course (H. Waldmann, P. Janning; Eds.) 2004, Wiley-VCH, Weinheim, 23-34.

39. "Single-Nucleotide-Specific PNA-Peptide Ligation on Synthetic and PCR DNA Templates"
S. Ficht, A. Mattes, O. Seitz*, J. Am. Chem. Soc. 2004, 126, 9970-9981.

38. "New isocysteine building blocks and chemoselective peptide ligation"
C. Dose, O. Seitz*, Org. Biomol. Chem. 2004, 2, 59-65.

37. "Homogenous DNA Detection"
O. Seitz, Bioorganic Chemistry Highlights II (C. Schmuck, H. Wennemers; Eds.), 2004, 311-328, Wiley-VCH, Weinheim.

36. "Thiazole orange as fluorescent universal base in PNA"
O. Köhler, O. Seitz*, Chem. Commun. 2003, 2938-2939.

35. "Polycyclic Aromatic DNA-Base Surrogates: High-affinity Binding to an Adenine-specific Base Flipping DNA Methyltransferase"
C. Beuck, I. Singh, A. Bhattacharya, W. Hecker, V. S. Parmar, O. Seitz*, E. Weinhold*, Angew. Chem. 2003, 115, 4088-4091; Angew. Chem. Int. Ed. 2003, 42, 3958-3960.

34. "Glycopeptides and Glycoproteins: Synthetic Chemistry and Biology"
O. Seitz, Carbohydrate based Drug Discovery (C.-H. Wong; Ed.), 2003, 169-214, Wiley-VCH, Weinheim.

33. "Synthesis of protein-nucleic acid conjugates by expressed protein ligation"
M. Lovrinovic, R. Wacker, H. Schroeder, O. Seitz, R. Seidel, M. Engelhard, R. Goody and C. M. Niemeyer*, Chem. Commun. 2003, 822-823.

32. "The chemical total synthesis of proteins"
O. Seitz in Organic Synthesis Highlights V (H.G. Schmalz, T. Wirth; Eds.) 2003, 368-383, Wiley-VCH, Weinheim.

31. "Transition-metal catalysed functionalisation of alkanes"
O. Seitz in Organic Synthesis Highlights V (H.G. Schmalz, T. Wirth; Eds.) 2003, 36-47, Wiley-VCH, Weinheim.

30. "Activating protecting groups for the solid phase synthesis and modification of peptides, oligonucleotides and oligosaccharides"
O. Seitz in Organic Synthesis Highlights V (H.G. Schmalz, T. Wirth; Eds.) 2003, 230-250, Wiley-VCH, Weinheim.

29. "N-(2-Boc-Aminoethyl)-N-(thymin-1-ylacetyl)glycine"
F. Münstermann, O. Seitz*, Electronic Encyclopedia of Reagents for Organic Synthesis.

28. "Local disruption of DNA-base stacking by bulky base surrogates"
I. Singh, W. Hecker, A. K. Prasad, V. S. Parmar, O. Seitz*, Chem. Commun. 2002, 500-501.

27. "Polymergebundene Liganden und Katalysatoren für die asymmetrische Synthese"
O. Seitz, Nachrichten aus Chemie und Technik, 2001, 49, 1419-1423.

26. "Sequence Fidelity of a PNA-based Ligation Reaction"
A. Mattes, O. Seitz*, Chem. Commun. 2001, 2050-2051.

25. "Convergent Strategies for the Attachment of Fluorescing Reporter Groups to Peptide Nucleic Acids in Solution and on Solid Phase"
O. Seitz*, O. Köhler, Chem. Eur. J. 2001, 7, 3911-3925.

24. "Mass-spectrometrical Monitoring of a PNA-based Ligation Reaction for the Multiplex Detection of DNA Single Base Mutations"
A. Mattes, O. Seitz*, Angew. Chem., 2001, 113, 3277-3280; Angew. Chem. Int. Ed. 2001, 40, 3178-3181.

23. "Totalsynthese von Phorboxazol"
O. Seitz, Nachrichten aus Chemie und Technik, 2001, 49, 1189-1195.

22. "Die cyclisierende Ablösung"
O. Seitz, Nachrichten aus Chemie und Technik, 2001, 49, 912-916.

21. "Übergangsmetall-katalysierte Funktionalisierung von Alkanen"
O. Seitz, Nachrichten aus Chemie und Technik, 2001, 49, 777-783.

20. "Die chemische Totalsynthese von Proteinen"
O. Seitz, Nachrichten aus Chemie und Technik, 2001, 49, 488-492.

19. "Synthetic Peptide Conjugates - Tailor-made Probes for the Biology of Protein Modification and Protein Processing" (Review)
O. Seitz*, I. Heinemann, A. Mattes, H. Waldmann, Tetrahedron 2001, 57, 2247-2277.

18. "Glycopeptide Synthesis and the Effect on Protein Structure and Activity" (Review)
O. Seitz, ChemBioChem. 2000, 4, 214-246.

17. "Synthesis of a Triply Phosphorylated Pentapeptide from Human t-Protein"
N. Kuder, T. Zelinski, T. Pathak, O. Seitz, H. Waldmann*, Bioorg.& Med. Chem. 2000, 8, 2433-2499.

16. "Solid Phase Synthesis of Doubly Labelled Peptide Nucleic Acids as Probes for the Real Time Detection of Hybridisation"
O. Seitz, Angew. Chem. 2000, 112, 3389-3392; Angew. Chem. Int. Ed. 2000, 39, 3249-3252.

15. "Chemically Modified Antisense Oligonucleotides - Recent Improvements of RNA Binding and Ribonuclease H Recruitment" (Highlight)
O. Seitz, Angew. Chem. 1999, 111, 3674-3677; Angew. Chem. Int. Ed. 1999, 38, 3466-3469.

14. "Solid Phase Synthesis of Protected Peptide Nucleic Acids"
O. Seitz, Tetrahedron Lett. 1999, 40, 4161-4164

13. "A Convergent Strategy for the Modification of Peptide Nucleic Acids (PNA). Novel Mismatch-Specific PNA-Hybridisation Probes."
O. Seitz*, F. Bergmann, D. Heindl, Angew. Chem. 1999, 111, 2340-2343; Angew. Chem. Int. Ed. 1999, 38, 2203-2206.

12. "Structural Study on O-Glycopeptides: Glycosylation-Induced Conformational Changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X Peptides of the Mucin Domain of MAdCAM-1"
W.-G. Wu, L. Pasternack, D.-H. Huang, K.M. Koeller, C.-C. Lin, O. Seitz, C.-H. Wong*, J. Am. Chem. Soc. 1999, 121, 2104-2417.

11. "New Protecting Group Strategies for the Solid Phase Synthesis and Modification of Peptides, Oligonucleotides and Oligosaccharides" (Highlight)
O. Seitz, Angew. Chem. 1998, 110, 3289-3291; Angew. Chem. Int. Ed. 1998, 37, 3109-3111.

10. "Glycosylation of Threonine of the Repeating Unit of RNA Polymerase II with - Linked N-Acetylglucosamine Leads to a Turnlike Structure"
E.E. Simanek, G.-H. Huang, L. Pasternack, T.D. Machajewski, O. Seitz, D.S. Millar, H.J. Dyson, C.-H. Wong*, J. Am. Chem. Soc. 1998, 120, 11567-11575.

9. "Solution- and Solid-Phase Synthesis of N-Protected Glycopeptide Esters of the Benzyl Type as Substrates for Subtilisin-Catalyzed Glycopeptide Couplings"
K. Witte, O. Seitz, C.-H. Wong*, J. Am. Chem. Soc. 1998, 120, 1979-1989.

8. "Sequence-dependent structural features of an O-linked sialyl-Lewis-X glycopeptide"
L.B. Pasternack, D.H. Huang, W.Q. Wu, K.M. Koeller, O. Seitz, C.H. Wong*, J. Molecular Graphics & Modelling, 1998, 16, 295.

7. "Enzymatic Hydrolysis of Hydrophilic Esters by Lipases in the Synthesis of Peptides and Glycopeptides"
M. Gewehr, P. Braun, O. Seitz, H. Kunz*, Peptides 1996 (Eds.: R. Ramage, R. Epton, The European Peptide Society 1998, Mayflower Scientific Ltd., Kingswinford) 257-258.

6. "Chemoenzymatic Solution- and Solid-Phase Synthesis of O-Glycopeptides of the Mucin Domain of MAdCAM-1. A General Route to O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X Peptides"
O. Seitz, C.-H. Wong*, J. Am. Chem. Soc. 1997, 119, 8766-8776.

5. "A Sequencing Strategy for the Localization of O-Glycosylation Sites of MUC1 Tandem Repeats by PSD-MALDI mass spectrometry"
S. Goletz, B. Thiede, F.-G. Hanisch, M. Schultz, J. Peter-Katalinic, S. Muller, O. Seitz, U. Karsten*, Glycobiology 1997, 7, 881-889.

4. "HYCRON, an Allylic Anchor for High-Efficiency Solid Phase Synthesis of Protected Peptides and Glycopeptides"
O. Seitz, H. Kunz*, J. Org. Chem. 1997, 62, 813-826.

3. "Use of the Allylic HYCRON Anchor in Solid Phase Peptide Synthesis"
M. Gewehr, H. Kunz, A. Lauterbach, B. Löhr, O. Seitz, Innovations and Perspectives in Solid Phase Synthesis, (Eds.: R. Epton; Mayflower Scientific Ltd., Birmingham), 1997, 17-120.

2. "Synthetic Tumor-Associated Glycopeptide Antigens"
Seitz , B. Liebe, P. Braun, K. von dem Bruch, H. Kunz*, Control Mechanisms of Carcigonesis (Eds.: J.G. Hengstler, F. Oesch; Mainz), 1996, 338.

1. "A Novel Allylic Anchor for Solid Phase Synthesis - Synthesis of Protected and Unprotected O-Glycosylated Mucin-Type Glycopeptides"
O. Seitz, H. Kunz*, Angew. Chem. 1995, 107901-904.