Publications
Prof. Dr. Christoph Arenz
1999
C. Arenz, A. Giannis
"Design and Synthesis of Modulators of Sphingolipid Biosynthesis" in U. Diederichsen et. Al. (Ed.) Bioorganic Chemistry, Highlights and New Aspects, Wiley-VCH, Weinheim, 1999, 225-231.
2000
C. Arenz, A. Giannis
"Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase" Angew. Chem. 2000, 112, 1498-1500; Angew. Chem. Int. Ed. 2000, 39, 1440-1442.
2001
C. Arenz, A. Giannis
"Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase" Eur. J. Org. Chem. 2001, 1, 137-140.C. Arenz, M. Thutewohl, O. Block, H. Waldmann, H.-J. Altenbach, A. Giannis
"Manumycin A and its Analogues Are Irreversible Inhibitors of Neutral Sphingomyelinase" ChemBioChem 2001, 2, 141-143.C. Arenz, M. Gartner V. Wascholowski, A. Giannis
"Synthesis and Biological Investigation of Scyphostatin Analogues as Inhibitors of Neutral Sphingomyelinase" Bioorg. Med. Chem. 2001, 11, 2901-2904.
2003
M. Diallo, C. Arenz, K. Schmitz, K. Sandhoff, U. Schepers
"RNA Interference: A new method to analyze the function of glycoproteins and glycosylating proteins. Knockout experiments with UDP-glucose/ceramide glucosyl-transferase as an example for its general application." Meth. Enzymol. 2003, 363, 173-190.C. Arenz, U. Schepers
"RNA Interference: from an ancient mechanism to a state of the art therapeutic application?" Naturwissenschaften 2003, 90, 345-359.M. Kölzer, C. Arenz, K. Ferlinz, N. Werth, S. Lansmann, K. Sandhoff
"The newly discovered cellular signalling molecule is a potent inhibitor of acid Sphingomyelinase" Biol. Chem. 2003, 384, 1293-1298.M. Diallo, C. Arenz, K. Schmitz, K. Sandhoff, U. Schepers
"Long endogenous dsRNA can induce complete gene silencing in mammalian cells and primary cultures" Oligonucleotides 2003, 13, 357-363.Published conference contributions
C. Arenz, A. Cryns, M. Diallo, K. Sandhoff, U. Schepers
"Analysis of skin glycosphingolipid metabolism by RNA interference in transgenic mice" Eur. J. Cell Biol. 2003, 82, 97.M. Diallo, C. Arenz, K. Schmitz, K. Sandhoff, U. Schepers
"Stable post transcriptional gene silencing of glucosylceramide-synthase by RNA interference in human cells" Eur. J. Cell Biol. 2003, 82, 98.K. Schmitz, C. Arenz, M. Diallo, A.Cryns, S. Hoffman, K. Sandhoff, U. Schepers
"New approaches to study protein function in mammalian cells and organisms Eur. J. Cell Biol. 2003, 82, 99-100.K. Schmitz, M. Diallo, C. Arenz, R. Mundegar, K. Sandhoff, U. Schepers
"Synthesis of a new carrier-system for transduction of siRNAs into cells for the local transient posttranscriptional gene silencing in mammals" Eur. J. Cell Biol. 2003, 82, 100.
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