Humboldt-Universität zu Berlin - Faculty of Mathematics and Natural Sciences - Department of Chemistry

Functionalized Magnetic Nanoparticles

Magnetite nanoparticles are developed wich are covered by organic shells bearing functional groups, such as reactive groups, biological and other recognition functions, catalytic units, metal compexing groups. The shells can be monomeric or polymeric. The nanoparticles are superparamagnetic and thus are interesting for various applications such as targeted drug delivery, hyperthermia, separation of biomaterials or toxic materials and as easily recyclable catalysts. The properties of the nanocomposites are investigated by TEM, SEM, HRTEM, FTIR spectroscopy and magnetization measurements.


Synthesis of magnetic nanoparticles covered with functionalized polypyrrole-shells

nanoparticles 1


Synthesis of magnetically tagged proline polyacrylates

nanoparticles 2
nanoparticles 3
nanoparticles 4


Synthesis of functionalized PPy-coated magnetite

nanoparticles 5


Synthesis of MNP 4 and CuAAC-mediated functionalization to MNP 6

nanoparticles 6


Selected Publications

Izabella Craciunescu, Anca Petran, Jürgen Liebscher, Ladislau Vekas, Rodica Turcu: "Synthesis and characterization of size-controlled magnetic clusters functionalized with polymer layer for wastewater depollution"
Mat. Chem. Phys., 2017, 185, 91-97, DOI 10.1016/j.matchemphys.2016.10.009

Monica Circu, Alexandrina Nan, Gheorghe Borodi. Jürgen Liebscher, Rodica Turcu: "Refinement of magnetic nanoparticles by coating with organic stabilizers"
Nanmaterials, 2016, 6, 228 (12 pages), DOI 10.3390/nano6120228

Alexander Bunge, Lidia Magerusan, Ion Morjan, Rodica Turcu, Gheorghe Borodi, Jürgen Liebscher: "Diazonium salt-mediated synthesis of new amino, hydroxy, propargyl, and maleinimido-containing superparamagnetic Fe@C nanoparicles as platforms for linking bio-entities or organocatalytic moieties"
J. Nanopart. Res., 2015, 17:379

Crina Socaci, Lidia Magerusan, Rodica Turcu, Jürgen Liebscher: "Developing novel strategies for the functionalization of core-shell magnetic nanoparticles with folic acid derivatives"
Mat. Chem. Phys., 2015, 162, 131-139./

Radoslaw Mrowczynski, Alexandrina Nan, Jürgen Liebscher: "Magnetic nanoparticle-supported organocatalysts an efficient way of recycling and reuse"
RSC Advances, 2014, 4, 5927-5952

Radoslaw Mrowczynski, Rodica Turcu, Cristian Leostean, Holger A. Scheidt, Jürgen Liebscher: "New versatile polydopamine coated functionalized magnetic nanoparticles"
Mat. Chem. Phys., 2013, 138, 295-302

Crina Socaci, Miriam Rybka, Lidia Magerusan, Alexandrina Nan, Rodica Turcu, Jürgen Liebscher: "Magnetite nanoparticles coated with alkyne-containing polyacrylates for click-chemistry"
J. Nanoparticle Res., 2013, 15:1747

Alexandrina Nan, Rodica Turcu, Jürgen Liebscher: "Magnetite-polylactic acid core-shell nanoparticles by ring opening polymerization under microwave irradiation"
J. Polymer Sci.. A: Polymer Chem., 2012, 50, 1485-1490

Sebastian Karsten, Alexandrina Nan, Rodica Turcu, J. Liebscher: "A New Access to Polypyrrole-Based Functionalized Magnetic Core-Shell Nanoparticles"
J. Polymer Sci. A: Polymer Chem., 2012, 50, 3986-3995

Radoslaw Mrowczynski, Lidia Rednik, Rodica Turcu, Jürgen Liebscher: "One-step ligand exchange reaction as an efficient way for functionalization of magnetic nanoparticles"
J. Nanoparticle Res., 2012, 14, 985

Zekarias Yacob, Alexandrina Nan, Jürgen Liebscher: "Proline-Functionalized Magnetic Core-Shell Nanoparticles as Efficient and Recyclable Organocatalysts for Aldol Reactions"
Adv. Synth. Cat., 2012, 354, 3259-3264

Sebastian Karsten, Alexandrina Nan, Jürgen Liebscher: "Linking applicatory functions to the 3-position of pyrrole by click chemistry"
Arkivoc, 2012, (ix), 204-219

S. Karsten, M. A. Ameen, S. I. Kalläne, A. Nan, R. Turcu, J. Liebscher: "A versatile method of tethering biomolecules to pyrrole – precursors for functionalized magnetic polypyrrole core-shell nanoparticles"
Synthesis, 2010, 3021-3028

Alexandrina Nan, Izabell Craciunescu, Attila Bende, Rodica Turcu, Detlef Reichert, Jürgen Liebscher "Synthesis and Structure Investigations of Functionalized Polypyrrole Copolymers"
J.Nanostruct.Polymer & Nanocomposites, 2008, 4, 3-12

Rodica Turcu, Alexandrina Nan, Izabell Craciunescu, Jürgen Liebscher, Ovidiu Pana, Doina Bica, Ladislau Vekas, Carmen Mijangos: "Comparative study of hybrid nanostructures of polymer-magnetic nanoparticles"
Journal of Optoelectronics and Advanced Materials, 2008, 9, 2237-2243

Alexandrina Nan, Izabell Craciunescu, Rodica Turcu, Detlef Reichert, Jürgen Liebscher: "Synthesis and characterization of new functionalised pyrrole copolymers"
Journal of Optoelectronics and Advanced Materials, 2008, 10, 2645

Alexandrina Nan, Izabell Craciunescu, Rodica Turcu, Ion Bratu, Doina Bica, Ladislau Vekas, Jürgen Liebscher: "Novel magnetic core shell Polypyrrole-Fe3O4 nanoparticles functionalized by peptides or albumine"
Arkivoc, 2008, 307-320