Humboldt-Universität zu Berlin - Faculty of Mathematics and Natural Sciences - Bioorganic Synthesis



June 2022

Dino Gluhacevic's and Magdalena Roth's paper is online. Congratulations! They introduce a loss-of-affinity principle to increase the catalytic efficiency of DNA-templated reactions.


Check out the epic review from Tim Bilbrough and Emanuele Piemontese on protein phosphorylation, which just got published in Chemical Society Reviews:

February 2022


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Yannic Altrichter defended his doctoral thesis on "Conditional synthesis and synergistic amplification of Smac-mimetic peptides with nucleic acids" with an excellent presentation and received a well-deserved "summa cum laude".
May 2022


Magdalena Roth defended her doctoral thesis on "RNA controlled phosphate cleavage reactions of nucleic acids" with "magna cum laude".Congratulations!


October 2021
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Natalia Loibl defended her PhD thesis on "Monitoring of microRNA maturation and its inhibition in living cells" .

Check how coiled coil-mediated covalent protein labeling has helped elucidate internalization of the chemerin receptor GPR1. Read:


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Saparmyrat Annamadov just arrived in our team. We are happy to have you. Sapar will be working on nucleic acid catalyzed cleavage reactions.






September 2021
Magdalena's paper on a self-immolative molecular beacon just appeared. Congratulations Magdalena!


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Read if you want to learn about a Molecular Beacon that self-distructs when exposed to blue light in presence of a DNA/RNA target.

Congrats Richard and Marvin. Your report on a RNA-templated benzanilide synthesis of a cancer drug derivative got published.
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Read for more details

August, 9th 2021

After all these difficulties with traveling in times  of pandemics, we are very happy to welcome our newest member
Dr. Pritam Ghosh in our group. Warmest welcome!

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Pritam will work on the development of viscosity-sensitive fluorescent probes for recognition of glycans on cell surface hydrogels.






July 2021

Congratulation Georgie!




Your paper on othogonal PNA tagging of protein on live cells got published. Thanks also to Katharina, Marc, Michael and Sebastion for your invaluable contributions. View the article:


Congratulation Yannic!





June 2021


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Henrik Petszulat successfully defended his PhD thesis on fluorogenic peptide ligation reactions


Congratulation Olaf and Sebastian!




Your great work on our new ligation auxiliary got published in Angewandte Chemie.

This is the first auxiliary which promotes native chemical ligation by base catalysis. Read the ASAP version: