Humboldt-Universität zu Berlin - Faculty of Mathematics and Natural Sciences - Bioorganic Synthesis

 

 

June 2022
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Dino Gluhacevic's and Magdalena Roth's paper is online. Congratulations! They introduce a loss-of-affinity principle to increase the catalytic efficiency of DNA-templated reactions.
https://pubs.acs.org/doi/10.1021/jacs.2c03188

 
 

Check out the epic review from Tim Bilbrough and Emanuele Piemontese on protein phosphorylation, which just got published in Chemical Society Reviews:

https://pubs.rsc.org/en/content/articlelanding/2022/CS/D1CS00991E

 

February 2022

 

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Yannic Altrichter defended his doctoral thesis on "Conditional synthesis and synergistic amplification of Smac-mimetic peptides with nucleic acids" with an excellent presentation and received a well-deserved "summa cum laude".
 
May 2022

 

Magdalena Roth defended her doctoral thesis on "RNA controlled phosphate cleavage reactions of nucleic acids" with "magna cum laude".Congratulations!

 

October 2021

 

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Natalia Loibl defended her PhD thesis on "Monitoring of microRNA maturation and its inhibition in living cells" .

Check how coiled coil-mediated covalent protein labeling has helped elucidate internalization of the chemerin receptor GPR1. Read: https://doi.org/10.1007/s00018-021-03894-8

 

 
 

 

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Saparmyrat Annamadov just arrived in our team. We are happy to have you. Sapar will be working on nucleic acid catalyzed cleavage reactions.

 

 

 

 

 

September 2021

 

Magdalena's paper on a self-immolative molecular beacon just appeared. Congratulations Magdalena!

 

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Read https://doi.org/10.1002/chem.202102600 if you want to learn about a Molecular Beacon that self-distructs when exposed to blue light in presence of a DNA/RNA target.


 
Congrats Richard and Marvin. Your report on a RNA-templated benzanilide synthesis of a cancer drug derivative got published.
 
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Read for more details
https://doi.org/10.1039/D1SC00513H.

 

August, 9th 2021

After all these difficulties with traveling in times  of pandemics, we are very happy to welcome our newest member
Dr. Pritam Ghosh in our group. Warmest welcome!

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Pritam will work on the development of viscosity-sensitive fluorescent probes for recognition of glycans on cell surface hydrogels.

 
July 2021  -  Congratulations Yannic!

 

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Read http://doi.org/10.1002/bip.23466

 

July 2021  -  Congratulations Georgie!

 

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Your paper on othogonal PNA tagging of protein on live cells got published. Thanks also to Katharina, Marc, Michael and Sebastion for your invaluable contributions. View the article: 

https://doi.org/10.1039/D1CB00126D

 
June 2021  -  Congratulations Olaf and Sebastian!

 

 

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Your great work on our new ligation auxiliary got published in Angewandte Chemie.

This is the first auxiliary which promotes native chemical ligation by base catalysis. Read the ASAP version:

https://doi.org/10.1002/anie.202107158

June 2021

 

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Henrik Petszulat successfully defended his PhD thesis

on fluorogenic peptide ligation reactions