Humboldt-Universität zu Berlin - Faculty of Mathematics and Natural Sciences - Bioorganic Synthesis

 

 

June 2022
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Dino Gluhacevic's and Magdalena Roth's paper is online. Congratulations! They introduce a loss-of-affinity principle to increase the catalytic efficiency of DNA-templated reactions.
https://pubs.acs.org/doi/10.1021/jacs.2c03188

 
 September 2022

 

Richard Houska defended his doctoral thesis on "RNA-templated synthesis of Bcr-Abl tyrosine kinase inhibitors" with "magna cum laude".Congratulations!

 

  

June 2022

Check out the epic review from Tim Bilbrough and Emanuele Piemontese on protein phosphorylation, which just got published in Chemical Society Reviews:

https://pubs.rsc.org/en/content/articlelanding/2022/CS/D1CS00991E

February 2022

 

Yannic Altrichter defended his doctoral thesis on "Conditional synthesis and synergistic amplification of Smac-mimetic peptides with nucleic acids" with an excellent presentation and received a well-deserved "summa cum laude".
 
May 2022

 

Magdalena Roth defended her doctoral thesis on "RNA controlled phosphate cleavage reactions of nucleic acids" with "magna cum laude".Congratulations!

 

October 2021
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Natalia Loibl defended her PhD thesis on "Monitoring of microRNA maturation and its inhibition in living cells" .

Check how coiled coil-mediated covalent protein labeling has helped elucidate internalization of the chemerin receptor GPR1. Read: https://doi.org/10.1007/s00018-021-03894-8

 

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Saparmyrat Annamadov just arrived in our team. We are happy to have you. Sapar will be working on nucleic acid catalyzed cleavage reactions.

 

 

 

 

 

September 2021
Magdalena's paper on a self-immolative molecular beacon just appeared. Congratulations Magdalena!

 

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Read https://doi.org/10.1002/chem.202102600 if you want to learn about a Molecular Beacon that self-distructs when exposed to blue light in presence of a DNA/RNA target.

 
Congrats Richard and Marvin. Your report on a RNA-templated benzanilide synthesis of a cancer drug derivative got published.
 
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Read for more details
https://doi.org/10.1039/D1SC00513H.

July 2021

Congratulation Georgie!

 

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Your paper on othogonal PNA tagging of protein on live cells got published. Thanks also to Katharina, Marc, Michael and Sebastion for your invaluable contributions. View the article: 

https://doi.org/10.1039/D1CB00126D

 

Congratulation Yannic!

 

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Read http://doi.org/10.1002/bip.23466

June 2021

 

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Henrik Petszulat successfully defended his PhD thesis on fluorogenic peptide ligation reactions

 

Congratulation Olaf and Sebastian!

 

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Your great work on our new ligation auxiliary got published in Angewandte Chemie.

This is the first auxiliary which promotes native chemical ligation by base catalysis. Read the ASAP version:

https://doi.org/10.1002/anie.202107158